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Pulse Rifle may refer to:
- M41A Pulse Rifle, an assault rifle used by the United States Colonial Marine Corps in the film Aliens.
- M41AE2 Heavy Pulse Rifle, a squad support weapon used by the USCM in the book Aliens: Colonial Marines Technical Manual.
- Lacrima 99 Shockrifle, sometimes referred to as the Pulse Rifle, an assault rifle used by the United Systems Military in the film Alien Resurrection.
- M41A/2 Pulse Rifle, an assault rifle used by the USCM in the video game Aliens vs. Predator.
- M41A Pulse Rifle MK2, an assault rifle used by the USCM in the video game Aliens: Colonial Marines.