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|Notable members:||Don Giovanni|
|Major activities:||Racketeering, weapons trafficking, drug trafficking, extortion, illegal gambling, loan sharking, money laundering, contract killing, bribery|
The Neonopolis Mafia were an Italian-American criminal gang that was active in Neonopolis in 2030. They were led by Don Giovanni. The Neonopolis Mafia were one of a number of gangs that had acquired stolen Yautja technology from Borgia Industries and was using that technology to wage gang warfare on the streets of Neonopolis.