Harper Prism logo
Headquarters: New York City, New York
Founded by: John Silbersack
Years active: 1993-1999
Major activities: Book publisher

HarperPrism was an imprint of HarperCollins based in New York City responsible for publishing science-fiction books and novels. It was established in 1993 by John Silbersack. HarperPrism was responsible for publishing Alien and Alien vs. Predator books and print media from 1995 to 1997.

When HarperCollins acquired Avon Books in 1999, the HarperPrism imprint was absorbed into the Avon Eos line.