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Alien3 for the Super Nintendo is very different from the Alien3 adaptations for other systems. The game consists of six stages, and in each, you are given a series of missions to complete that include rescuing prisoners; repairing pipes, fuses, and junction boxes; welding doors shut; and destroying Xenomorph Eggs, as well as the Xenomorph Queen. Once you have accomplished all missions in a stage, you move on to the next stage where you will receive new mission objectives. Missions are outlined via a terminal, and a series of blueprints help you navigate your way through the complex.
Making your job difficult are several types of Xenomorph, which can be killed using Pulse Rifles, grenade launchers and flamethrowers (which comes in three variants). Med-kits can be picked up that will increase your health.